Searchable abstracts of presentations at key conferences in endocrinology

ea0044ep27 | (1) | SFEBES2016

Maternal hypercalcaemia due to CYP24A1 loss of function mutations

Upton Thomas , Florkowski Chris , Phillips Ian , Hunt Penny

Background: Significant changes in calcium metabolism occur during normal pregnancy to meet the needs of the growing fetus. These include a rise in 1,25-dihydroxyvitamin D (1,25-(OH)D2 and consequent suppression of parathyroid hormone (PTH). In spite of this, maternal hypercalcaemia is very uncommon and should prompt further investigation.Clinical case: A 24-year-old primigravida woman was referred for assessment of maternal hypercalcaemia. Sh...